Dr. Chandra's research focuses on three aspects of COPD:
How does a disease of the lung (COPD) produce varied systemic comorbidities such as atherosclerosis and kidney dysfunction? This research uses a translational approach, and focuses on the study of inflammatory and autoimmunity processes as novel mechanisms for systemic vascular injury in COPD.
Are there as yet undefined systemic manifestations of COPD and how can these be identified? This work includes the first description of a novel emphysema kidney injury phenotype.
How can phenomic data on patients with COPD be analyzed and interpreted using advanced computational methods to understand disease heterogeneity?