Find a Clinical Trial | American Lung Association

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ELEVATE

The ELEVATE study is evaluating the safety and efficacy of the investigational drug LYT-100 (deupirfenidone) in people living with IPF. LYT-100 has been modified in a way that slows down metabolism of the drug compared to pirfenidone and has demonstrated improved tolerability compared to pirfenidone in previous studies.

Exablate

The primary objective is to evaluate the safety and efficacy of blood brain barrier disruption using the Exablate Type 2 system in adult subjects with brain metastases of NSCLC origin that are either undergoing or have planned standard of care pembrolizumab monotherapy as compared to subjects that are undergoing standard of care pembrolizumab without Exablate blood brain barrier disruption.

Gates MRI- COD-01-T01-01 Amendment 1

A randomized, controlled, Phase 2b study to evaluate safety and efficacy of rivaroxaban(Xarelto®) for high risk people with mild COVID-19.

HARBOR Study

The HARBOR Study is evaluating the safety and effectiveness of a potential medicine (HZN-825) that may slow disease progression in participants with idiopathic pulmonary fibrosis (IPF).

ICoN-1

This clinical trial is designed to compare the efficacy and safety of Clofazimine Inhalation Suspension versus placebo when added to guideline-based therapy (GBT)

IMPALA2

To discover whether molgramostim (inhaled GM-CSF) is safe to take and can help to reduce the symptoms of (autoimmune pulmonary alveolar proteinosis ) aPAP.

Improving Medication Adherence with Telehealthcare Medication Therapy Management to Change Health Outcomes in Adolescents and Young Adults with Asthma (MATCH)

The ACRC network is studying whether having regular telehealth appointments with a pharmacist using a study provided tablet or a person’s smart phone or computer will help adolescents and young adults with asthma to gain control of asthma symptoms and improve inhaler effectiveness.

INSIGNIA PH-COPD

Phase 2a Randomized, Placebo-Controlled Clinical Study to Evaluate the Efficacy and Safety of MK-5475 in Adults With Pulmonary Hypertension Associated With Chronic Obstructive Pulmonary Disease.

KEYLYNK-012

This study is looking at how pembrolizumab with chemotherapy and radiation followed by pembrolizumab plus olaparib (or placebo for olaparib) works compared to chemotherapy and radiation followed by durvalumab.

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