Study Name:
A Phase III, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Patients With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

Targeted Disease(s):
Lung Cancer

Purpose of Study:

The purpose of this study is to evaluate the efficacy and safety of divarasib and pembrolizumab compared with pembrolizumab and pemetrexed and carboplatin or cisplatin, for the first-line treatment of adult participants with KRAS G12C-mutated, advanced or metastatic non squamous non-small cell lung cancer (NSCLC).

Study Dates:
August 1, 2025 - October 31, 2030

Type of Study:
Pre-Market

Study Design:
Controlled Design

Study Location:
Nationwide

Funding Source:
F. Hoffmann-La Roche Ltd

ClinicalTrails.gov Identifier:
NCT06793215

https://clinicaltrials.gov/study/NCT06793215

Register for Trial
Fight For Air Climb - Cleveland, OH
Cleveland, OH | Mar 01, 2026
Fight For Air Climb - Columbus, OH
Columbus, OH | Mar 22, 2026